How Blockers Affect GTO Bluffing and Bluff Catching

Short Answer
Blockers affect bluffing and bluff catching by changing how many combinations the opponent can hold. Good bluffs block strong calls. Good bluff catchers often block value while not blocking natural bluffs.
Blockers In Bluffing
Holding an ace or king can reduce the opponent's strongest continuing combinations. A suited ace used as a 4-bet bluff gains value not only from playability but also from blocking AA and AK.
Blockers In Bluff Catching
When bluff catching, you want fewer opponent value combos and many available bluff combos. If your hand blocks the opponent's missed draws, calling can become worse.
Common Misunderstanding
Blockers do not decide actions alone. A bad hand with a blocker can still be a poor bluff if it lacks fold equity or future equity. Blockers are one part of the EV puzzle.
Decision Steps
- List the opponent's strongest value combos.
- Check whether your hand removes those combos.
- List the opponent's natural bluffs.
- Avoid bluff catching with hands that block too many bluffs.